409 E Main Street

Brenham, TX 77833, USA

979-221-2051

stay@mainsthouse.com

Just a short walk from the Brenham Heritage Museum, Main Street House offers a fresh, wellness-focused bed-and-breakfast experience in historic downtown Brenham. This thoughtfully designed, chemical-free property features five contemporary guest rooms with king-size beds, spa-quality bedding, locally roasted coffee, and snacks available throughout your stay. Guests enjoy a relaxing, adults-focused atmosphere, local touches throughout the home, and easy access to Brenham’s restaurants, shopping, and entertainment.

As a valued Museum Community Partner, Main Street House guests receive discounted admission to the Brenham Heritage Museum.